WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: LAB 18 - USING ANTIMICROBIAL CHEMOTHERAPY TO CONTROL MICROORGANISMS, Using antimicrobial chemotherapy to control microorganisms definitions antimicrobial chemotherapeutic chemicals, Using antimicrobial chemotherapy to control microorganisms definitions antimicrobial chemotherapy, Using antimicrobial chemotherapy to control microorganisms mechanisms of microbial resistance to chemotherapeutic agents Altering the target site in the bacterium to reduce or block binding of the antibiotic, e.g., producing a slightly altered ribosomal subunit that still functions but to which the drug can't bind., selective toxicity definition The agent used must inhibit or kill the microorganism in question without seriously harming the host., cidal definition An agent that is cidal in action will kill microorganisms and inactivate viruses., automated tests description Measures the inhibitory effect of the antimicrobial agents in a liquid medium by using light scattering to determine growth of the test organism., antibiotics definition Substances produced as metabolic products of one microorganism which inhibit or kill other microorganisms. (Most antibiotics today are semisynthetic.), Using antimicrobial chemotherapy to control microorganisms mechanisms of microbial resistance to chemotherapeutic agents Developing an alternate metabolic pathway to by-pass the metabolic step being blocked by the antimicrobial agent, e.g., overcoming drugs that resemble substrates and tie-up bacterial enzymes., Using antimicrobial chemotherapy to control microorganisms antibiotic susceptibility testing tube dilution tests, Using antimicrobial chemotherapy to control microorganisms modes of action Alter 30S or 50S bacterial ribosomes blocking translation., Using antimicrobial chemotherapy to control microorganisms modes of action Inhibit peptidoglycan synthesis causing osmotic lysis., broad-spectrum agent definition Effective against a variety of both Gram-positive and Gram-negative bacteria., Using antimicrobial chemotherapy to control microorganisms definitions static, the agar diffusion test (Bauer-Kirby test) description In this test, the in vitro response of bacteria to a standardized antibiotic-containing disc has been correlated with the clinical response of patients given that drug., Using antimicrobial chemotherapy to control microorganisms definitions cidal, Alter the bacterial cytoplasmic membrane causing leakage of cellular needs. examples Polymyxin B, amphotericin B, nystatin, imidazoles, Inhibit peptidoglycan synthesis causing osmotic lysis. examples Penicillins, cephalosporins, carbapenems, monobactems, carbacephem, glycopeptides, bacitracin, Using antimicrobial chemotherapy to control microorganisms definitions broad-spectrum agent, narrow-spectrum agent definition Effective against just Gram-positive bacteria, just Gram negative bacteria, or only a few species., Alter 30S or 50S bacterial ribosomes blocking translation. examples Aminoglycosides, tetracyclines, lincomycin, clindamycin, macrolides, oxazolidinones, streptogramins